Trends in lower extremity peripheral arterial disease treatments and prognosis: a 10 years' experience in single center.

Tianyu MA; Yongquan GU; Email: GUYQ66@ALIYUNCOM; Lianrui GUO; Xuefeng LI; Zhu TONG; Jianming GUO

Return

Trends in lower extremity peripheral arterial disease treatments and prognosis: a 10 years' experience in single center.

Author: Tianyu MA ¹ ; Yongquan GU ² ; Email: GUYQ66@ALIYUN.COM. ; Lianrui GUO ¹ ; Xuefeng LI ¹ ; Zhu TONG ¹ ; Jianming GUO ¹
Author Information

1. Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
2. Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
Publication Type:Journal Article
MeSH: Humans; Ischemia; Limb Salvage; Lower Extremity; pathology; Peripheral Arterial Disease; diagnosis; surgery; therapy; Prognosis; Retrospective Studies; Risk Factors; Stem Cell Transplantation; Survival Rate; Treatment Outcome; Vascular Grafting; Vascular Patency
From: Chinese Journal of Surgery 2015;53(4):305-309
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo analyze the trends in treatments of lower extremity peripheral arterial disease and their prognosis in the recent 10 years.
METHODSClinical data of inpatients with lower extremity peripheral arterial disease who received surgical treatments in Xuanwu Hospital from January 2002 to December 2011 were analyzed retrospectively. Patients were stratified into two groups (group 1: from 2002 to 2006, group 2: from 2007 to 2011). The demographics, risk factors, clinical presentation, lesion anatomy, therapies, limb salvage and survival were observed. χ(2) test, Fisher exact test, and t test were used to compare the data between the two groups.
RESULTSFrom 2002 to 2006, 170 limbs (47.49%) underwent conventional bypass surgery, 72 limbs (20.11%) underwent endovascular interventions and the rest 116 limbs (32.40%) received stem cell treatment. While from 2007 to 2011, the percentages were 18.49%, 68.73%, 8.27%, respectively. Furthermore, gene-based drug appeared, 67 limbs (4.51%) underwent the new treatment. Former group had decreased limb salvage rates compared with latter group (87.15% vs. 93.41%, χ(2)=15.71, P=0.000). However, survival rates did not differ from the two groups (84.67% vs. 84.31%, χ(2)=0.02, P=0.880).
CONCLUSIONWith the appearance of new medical instruments and operating methods, the percentage of the patients with lower extremity peripheral arterial disease receive endovascular interventions increases, with a improved limb salvage rates.