A Case of Polymyositis associated with Hepatitis B infection.
- Author:
Sang Kun SIN
1
;
In Soo JOO
;
Byung In HAN
;
Ji Man HONG
;
Seong Yul JOO
;
Jang Hee KIM
Author Information
1. Department of Neurology, College of Medicine, Ajou University, Korea. isjoo@madang.ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Polymyositis;
Hepatitis;
Hepatitis B virus
- MeSH:
Autoimmunity;
Hepatitis B virus;
Hepatitis B*;
Hepatitis*;
Immunity, Cellular;
Korea;
Molecular Mimicry;
Muscle Proteins;
Muscle Weakness;
Myalgia;
Myositis;
Polymyositis*
- From:Journal of the Korean Neurological Association
2002;20(3):315-317
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Polymyositis(PM) is one of idiopathic inflammatory myopathy, characterized by proximal muscle weakness, myalgia and muscle enzyme elevation. Currently the main pathogenesis is well documented, the cell-mediated immunity. We experienced a case of polymyositis associated with hepatitis, developed after hepatitis B virus(HBV) infection. This virus-induced autoimmunity seems to result from the cross-reactivity between muscle protein and B-viral antigen, so called antigenic mimicry. This relation of PM and HBV is more significant in Korea because of the epidemicity of HBV infection.
