Research progress on the clinical value of Ki-67 in breast cancer and its cut-off definition.
- Author:
Qing CHEN
1
;
Kejin WU
2
;
Email: KEJINWU@163.COM.
Author Information
1. Department of General Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200092, China.
2. Department of General Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200092, China
- Publication Type:Journal Article
- MeSH:
Breast Neoplasms;
diagnosis;
Humans;
Ki-67 Antigen;
analysis;
Prognosis
- From:
Chinese Journal of Surgery
2015;53(8):634-637
- CountryChina
- Language:Chinese
-
Abstract:
Ki-67 has an important application value in clinical practice. However, it is still a little tough in clinical application because of the debate on the cut-off definition of Ki-67 index. This review summarizes most studies on the prognostic and predictive value of Ki-67, analyzes the reasons for the discrepancies among the studies cited, and presents the necessity and clinical significance of scientifically defining the cut-off of Ki-67 index, providing a theoretical basis for Ki-67 in clinical application.
