Prostate stem cell antigen and related cancers.
- Author:
Yong SHU
1
;
Danning SUN
Author Information
1. Center of Urology & Nephrology, 324th Hospital of PLA, Chongqing 400020, China. shuu71@sina.com.cn
- Publication Type:Journal Article
- MeSH:
Antigens, Neoplasm;
GPI-Linked Proteins;
Humans;
Immunotherapy;
Male;
Membrane Glycoproteins;
analysis;
genetics;
immunology;
Neoplasm Proteins;
analysis;
genetics;
immunology;
Pancreatic Neoplasms;
diagnosis;
Prostatic Neoplasms;
diagnosis;
Urinary Bladder Neoplasms;
diagnosis
- From:
National Journal of Andrology
2004;10(5):382-384
- CountryChina
- Language:Chinese
-
Abstract:
Prostate stem cell antigen (PSCA) is a cell surface antigen expressed in normal prostate and overexpressed in cancers associated with prostate, bladder and pancreas. The sensitivity of PSCA labeling is higher than PSA in prostate cancer. PSCA can be used in the preparation of protein vaccine and nucleic acid vaccine. Further studies are required to confirm its safety and efficacy as a diagnostic means.