Present situation in the study of antisperm antibodies.
- Author:
Guangwei LI
1
;
Guanghui DU
;
Weimin YANG
Author Information
1. Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China. guangwei30@163.com
- Publication Type:Journal Article
- MeSH:
Antibodies;
immunology;
Humans;
Immunoglobulin Isotypes;
immunology;
Male;
Reproduction;
Spermatozoa;
immunology
- From:
National Journal of Andrology
2004;10(5):385-390
- CountryChina
- Language:Chinese
-
Abstract:
Immune factors account for 5%-15% of male infertility. Because of the diversity in molecular weight, structure and location, sperm antigens play different roles in immune infertility. Antisperm antibodies (AsAb) influence sperm function not only by direct action, but also by changing the local microenvironment indirectly. This paper reviews the progress in the studies of the implication of human sperm antigens, the function, mechanisms, categories and titer of AsAb in male infertility.
