Effects of reproductive hormones on spermatogenesis.
- Author:
Yugui CUI
1
;
Ziqing CHEN
;
Jiahao SHA
Author Information
1. Key Laboratory, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China. cuiygui@njmu.edu.cn
- Publication Type:Journal Article
- MeSH:
Androgens;
physiology;
Apoptosis;
Contraception;
Follicle Stimulating Hormone;
physiology;
Humans;
Luteinizing Hormone;
physiology;
Male;
Spermatogenesis
- From:
National Journal of Andrology
2004;10(6):465-469
- CountryChina
- Language:Chinese
-
Abstract:
Spermatogenesis, a continuous course of cell proliferation and differentiation, depends on reproductive hormones. FSH and LH-induced T are the main hormones regulating spermatogensis. Intratesticular T is one of the key factors in maintaining spermatogenesis, while FSH is just as important for origination and maintenance of normal spermatogenesis. Sertoli cells are the pivot of hormonal regulation. Interestingly, these reproductive hormones also regulate sperm cell apoptosis spermatogenesis. Further studies on the hormonal regulation of spermatogenesis provide a base for the development of safe and recoverable contraceptives for males.
