Genetic polymorphism of 9 STR loci in Korean population of Mudanjiang.
- Author:
Xiao-bo BU
1
;
Jie SONG
;
Yan-long HAN
;
Shu-jie ZHANG
;
Song-bin FU
Author Information
- Publication Type:Journal Article
- MeSH: Amplified Fragment Length Polymorphism Analysis; Asian Continental Ancestry Group; Humans; Korea; Microsatellite Repeats; genetics; Polymorphism, Genetic; genetics
- From: Chinese Journal of Medical Genetics 2008;25(3):348-351
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the genetic polymorphism of 9 short tandem repeats (STR) gene loci, namely CSFIPO, TPOX, TH01, D16S539, D7S820, D13S317, F13A01, FESFPS and vWA in Chinese Korean population in Mudajiang area.
METHODSAmplified fragment length polymorphism (Amp-FLP) method was used to get the allele frequency distribution.
RESULTSThe genotype distributions of the 9 STR loci are conformed to Hardy-Weinberg equilibrium by chi(2) test analysis. The total accord frequency, the accumulated total discrimination power and the the accumulative excluding probability of paternity were calculated.
CONCLUSIONThe result suggested that all 9 gene loci have high power of excluding probability of paternity and individual identification. They can be used in paternity testing and individual identification for forensic medicine. The gene frequencies of CSFIPO, TPOX and TP01 gene loci have significant differences between the Korean population in Mudanjiang area and those in Yanji area, but there is no difference in gene loci of D7S820, D17S317 and vWA.
