A Case of Rheumatoid Arthritis Accompanied by Thrombotic Thrombocytopenic Purpura.
10.3904/kjm.2015.89.1.122
- Author:
Sung Min KANG
1
;
Ji Hyun LEE
;
In Hye KU
;
Hae Koo KIM
;
Kyoung Sik NAM
;
Suk Ki PARK
Author Information
1. Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center, Busan, Korea. ete@lycos.co.kr
- Publication Type:Case Report
- Keywords:
Thrombotic thrombocytopenic purpura;
Rheumatoid arthtiris;
Plasmapheresis
- MeSH:
Anemia, Hemolytic;
Arthritis, Rheumatoid*;
Autoimmune Diseases;
Blood Coagulation Disorders;
Brain;
Fever;
Heart;
Kidney;
Neurologic Manifestations;
Plasmapheresis;
Pregnancy;
Purpura, Thrombotic Thrombocytopenic*;
Renal Insufficiency;
Sepsis;
Thrombocytopenia;
Tympanoplasty
- From:Korean Journal of Medicine
2015;89(1):122-126
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Thrombotic thrombocytopenic purpura (TTP) is a blood coagulation disorder that damages numerous organs, including the kidney, heart and brain. Features indicative of TTP include thrombocytopenia, microangiopathic hemolytic anemia, neurologic symptoms, kidney failure and fever. Infections, toxins, pregnancy and, rarely, autoimmune diseases are all known to be associated with TTP. We encountered a rare case of rheumatoid arthritis accompanied by TTP following tympanoplasty. The patient's confusion, thrombocytopenia and renal failure all improved after plasmapheresis and high-dose glucocorticoid therapy, but she eventually expired due to sepsis. We report on this case herein and also review the relevant literature.
