Analysis of the genetic polymorphisms of 15 autosomal short tandem repeat in a Han population of Shandong.
- Author:
Jianpin TANG
1
;
Jian ZHANG
;
Bo HU
;
Fenghui JIANG
;
Xiaojun YU
Author Information
- Publication Type:Journal Article
- MeSH: Asian Continental Ancestry Group; genetics; Chromosomes, Human; genetics; Ethnic Groups; genetics; Female; Forensic Genetics; Gene Frequency; Genome, Human; genetics; Genomics; Heterozygote; Humans; Male; Microsatellite Repeats; genetics; Polymorphism, Genetic
- From: Chinese Journal of Medical Genetics 2008;25(6):715-717
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo obtain population genetic data at 15 short tandem repeat(STRs) in Shandong Han population.
METHODSFifteen STRs were genotyped in 200 unrelated individuals from Shandong Han population using Identifiler(TM) Kit.
RESULTSIn this Shandong Han population, the observed heterozygosities of the 15 loci ranged from 0.605 to 0.882, and the expected heterozygosities were 0.625-0.862, the polymorphic information contents ranged from 0.57 to 0.85, the discrimination powers ranged from 0.795 to 0.958, and the exclusion probabilities ranged from 0.297 to 0.758. The non-differentiation exact P values at TPOX loci were more than 0.05 between Shandong and Han population of Henan, Jilin, and Jiangsu. The non-differentiation exact P values between Shandong Han population and others populations were more than 0.05 at others loci. The P value at D13S317 was more than 0.05 between Shandong Han population and Ewenki population.
CONCLUSIONThese loci are polymorphic in Shandong Han population, and the discrimination powers and exclusion probabilities were high in the 15 STRs except TPOX and TH01.
