Macrostructure of sleep in patients with vascular cognitive impairment-no dementia.
- Author:
Mu-feng ZHU
1
;
Li-ying DENG
;
Li-min GONG
;
Hao LIU
;
Yong-min DING
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Case-Control Studies; Cognition Disorders; diagnosis; etiology; physiopathology; Dementia, Vascular; diagnosis; Female; Humans; Male; Middle Aged; Polysomnography; Sleep; physiology; Sleep Stages; Sleep Wake Disorders; etiology; Stroke; complications
- From: Journal of Southern Medical University 2011;31(2):295-298
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the sleep structure in patients with vascular cognitive impairment-no dementia (VCI-ND) and its differences from that of normal individuals.
METHODSThe whole night sleep record of 20 patients with VCI-ND were monitored by 32-head video-taped polysomnographic system, and the results were compared with the data of 20 normal subjects.
RESULTSCompared with normal subjects, patients with VCI-ND showed significantly reduced total sleep duration, increased waking times, increased stage 1 sleep, decreased stage 2 sleep, decreased stage 3 sleep, decreased rapid eye movement stage (REM) and reduced sleep efficiency.
CONCLUSIONIncreased light sleep as well as decreased slow-wave stage 3-4 sleep and decreased REM stage may be a specific electroneurophysiologic marker for VCI-ND, but large-sampled multi-centered randomized controlled trial is necessary to test the validity of these features as specific markers for screening and early diagnostic purposes.
