Risk factors of premature rupture of membranes with neonatal infection: a single-center study.
- Author:
Jin JIN
1
;
Yan ZHANG
;
Zhi-jian WANG
;
Mei ZHONG
;
Yan-hong YU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Case-Control Studies; Female; Fetal Membranes, Premature Rupture; epidemiology; microbiology; Humans; Infant, Newborn; Infant, Newborn, Diseases; epidemiology; microbiology; Infection; complications; epidemiology; Pregnancy; Retrospective Studies; Risk Factors; Young Adult
- From: Journal of Southern Medical University 2011;31(3):465-468
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the high-risk factors of premature rupture of membranes (PROM) with neonatal infection and explore their clinical significance.
METHODSForty-two cases of PROM with neonatal infections were retrospectively analyzed for the risk factors with another 42 PROM cases matched for gestational age without neonatal infections as the control group. The relations of gestational age, time from membrane rupture to delivery, mode of delivery, placental pathology, maternal serum C-reactive protein concentration, leukocyte and neutrophil values to neonatal infections were analyzed.
RESULTSThe time from membrane rupture to delivery was significantly longer and the incidence of chorioamnionitis significantly higher in the study group (P<0.05). Meningitis and neonatal sepsis occurred at a significantly higher incidence in preterm PROM group (P<0.05).
CONCLUSIONAn appropriate extension of the gestation weeks and timely termination of pregnancy after dynamic monitoring of the biochemical changes and identification of the signs of infection are important to reduce the incidence of neonatal infection.
