Therapeutic effect of subtotal gastrectomy and Roux-en-Y gastrojejunostomy on type 2 diabetes mellitus in non-obese patients.
- Author:
Chao FENG
1
;
Ruo-quan YAO
;
Fei-zhou HUANG
;
Wan-pin NIE
;
Xun-yang LIU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Anastomosis, Roux-en-Y; Diabetes Mellitus, Type 2; surgery; Female; Gastrectomy; Humans; Male; Middle Aged; Obesity; Postoperative Period; Retrospective Studies; Treatment Outcome
- From: Journal of Southern Medical University 2011;31(3):551-553
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the therapeutic effect of Roux-en-Y anastomosis following subtotal gastrectomy on type 2 diabetes mellitus (T2DM) in non-obese patients.
METHODSWe performed a retrospective analysis of 16 non-obese patients with T2DM undergoing Roux-en-Y anastomosis following subtotal gastrectomy for stomach cancer and upper gastrointestinal tract ulcer.
RESULTSAll the patients were followed up for 6 months after the surgery. Roux-en-Y gastrojejunostomy significantly lowered the levels of fasting plasma glucose (FPG), 2 h postprandial plasma glucose (2hPG), and glycated hemoglobin (HbA1c)(P<0.05). Of these patients, 8 (50%) achieved adequate glycemic control without antidiabetic medication and 5 (31.25%) showed obvious improvement. The total effectiveness rate of the surgery was 81.25%.
CONCLUSIONRoux-en-Y gastrectomy can effectively ameliorate the diabetic symptoms and might serve as a new treatment option for T2DM in non-obese patients.
