Chemical constituents from Corydalis yanhusuo.
- Author:
Tiantian HU
1
;
Xue ZHANG
;
Shizhong MA
;
Yiyu CHENG
;
Xinsheng YAO
Author Information
- Publication Type:Journal Article
- MeSH: Alkaloids; chemistry; Corydalis; chemistry; Drugs, Chinese Herbal; chemistry
- From: China Journal of Chinese Materia Medica 2009;34(15):1917-1920
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents from the 60% ethanol extract of Corydalis yanhusuo.
METHODThe chemical constituents were separated and purified by various chromatographic techniques, and their structures were elucidated by chemical evidence and spectroscopic analysis.
RESULTNine alkaloids were obtained and determined as 7-formyldidehydroglaucine (1), nantenine (2), (+)-O-methylbulbocapnine (3), d-corydaline (4), tetrahydrocoptisine (5), 8-oxocoptisine (6), palmatine (7), tetrahydropalmatine (8), and dehydrocorydaline (9), respectively.
CONCLUSIONCompound 1 was obtained from natural products for the first time, and its NMR data were firstly reported. Compound 3 was reported from Papaveraceae for the first time, and compound 6 was firstly reported from Corydalis yanhusuo.