Compatibility chemistry of acid-alkaline pair medicine of Dahuang and Huangbai in Dahuang Xiaoshi decoction.
- Author:
Miaorong PEI
1
;
Xiujun DUAN
;
Xiangping PEI
Author Information
- Publication Type:Journal Article
- MeSH: Acids; analysis; Alkalies; analysis; Drugs, Chinese Herbal; chemistry; Phellodendron; chemistry; Rheum; chemistry
- From: China Journal of Chinese Materia Medica 2009;34(18):2312-2315
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo determine the change pattern of alkaline and acid components of Dahuang and Huangbai amoung different combinations in Dahuang Xiaoshi decotion.
METHODThe contents of anthraquinones and berberine were determined by HPLC in samples of Dahuang extracts, Huangbai extracts, Dahuang and Huangbai pair medicine extracts, and extracts of whole recipe.
RESULTThe contents of anthraquinones and berberine were decreased with the changes of combinations: from component medicinal material alone to pair medicines, and to whole recipe. the change pattern was more apparent in water decoctions than in ethanol extracts.
CONCLUSIONThe contents of alkaline and acid components are changed with different extract methods and different combinations.
