A comparative research on quality of Vitmin C Yinqiao tablets from different manufacturers.
- Author:
Wei-nan ZHANG
1
;
Yu XIANG
;
Yuan-yuan JIANG
;
Zhuo-ming LI
;
Zhi-hua ZHANG
;
Hua ZHANG
;
Li LI
Author Information
- Publication Type:Journal Article
- MeSH: Arctium; chemistry; Ascorbic Acid; chemistry; Chlorogenic Acid; analysis; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; chemistry; isolation & purification; standards; Furans; analysis; Lignans; analysis; Lonicera; chemistry; Plants, Medicinal; chemistry; Quality Control; Tablets
- From: China Journal of Chinese Materia Medica 2007;32(22):2364-2367
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the different manufacturers Vitmin C (Vc) Yinqiao tablets, and the quality of the analysis of the problem, to provide a theoretical basis for the correct evaluation of the quality of medicines and improving the standard drugs.
METHOD11 manufacturers of 18 batches of samples for determination of the weight of the core tablets, powder samples were observed with microscope, determination of Vc, and the establishment of the Vc Yinqiao tablets HPLC method for determination of chlorogenic acid and arctigenin, chlorogenic acid and arctigenin in the samples were measured and compared.
RESULTThere is a big difference of microscope and various measured results in different manufacturers products.
CONCLUSIONBecause different manufacturers to produce the same, there are big differences in the quality of the products.