Effect of baicalin on in vivo anti-virus.
- Author:
Zheng-yun CHU
1
;
Ming CHU
;
Yu TENG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Antiviral Agents; isolation & purification; therapeutic use; Female; Flavonoids; isolation & purification; therapeutic use; Influenza A Virus, H1N1 Subtype; drug effects; Lung; drug effects; pathology; virology; Male; Mice; Orthomyxoviridae Infections; drug therapy; virology; Phytotherapy; Plants, Medicinal; chemistry; Pneumonia, Viral; drug therapy; virology; Random Allocation; Scutellaria baicalensis; chemistry; Treatment Outcome
- From: China Journal of Chinese Materia Medica 2007;32(22):2413-2415
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEThis study is about the in vivo antivirus effect of baicalin.
METHODAdopting in vivo experiment, we administered one group of mice 2 days before infected with influenza virus (A/FM/1/47) , while administer the other group with baicalin one day after infected, to observe the effect of baicalin in protecting and curing mice against influenza virus.
RESULTBaicalin can obviously prolong the survival time of mice infected with influenza virus (A/FM/1/47) (P <0.01), eliminate the influenza virus in lung, reduce the hemagglutination tite and infectivity in pulmo, and reverse mice's pneumonic pathological changes.
CONCLUSIONBaicalin can obviously counteract influenza virus.
