Tpeak-Tend interval and risk of cardiac events in patients with Brugada syndrome.
- Author:
Jin-feng WANG
1
;
Qi-jun SHAN
;
Bing YANG
;
Ming-long CHEN
;
Jian-gang ZOU
;
Chun CHEN
;
Dong-jie XU
;
Ke-jiang CAO
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Brugada Syndrome; diagnosis; physiopathology; Electrocardiography; Humans; Male; Middle Aged; Risk Factors; Ventricular Fibrillation; diagnosis; physiopathology
- From: Chinese Journal of Cardiology 2007;35(7):629-632
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the possible association between Tpeak-Tend (Tp-e) interval in surface standard ECG and cardiac events in patients with Brugada syndrome (BrS).
METHODTp-e interval in surface standard ECG was compared between BrS patients (n = 23, all males) and paroxysmal supraventricular tachycardia (PSVT) patients (n = 20, all males) as well as between BrS patients with (n = 16) or without (n = 7) cardiac events.
RESULTSThere was significant difference in Tp-e interval between BrS patients and PSVT patients [(109.57 +/- 22.86) ms vs. (88.50 +/- 13.08) ms, P < 0.05]. Tp-e interval was also significantly longer in BrS patients with cardiac events (syncope, clinical ventricular fibrillation and induced VF during electrophysiological study) than BrS patients without cardiac events [(118.12 +/- 20.40) ms vs. (90.00 +/- 15.27) ms, P < 0.05] while Tp-e interval was similar between BrS patients without cardiac events and PSVT patients (P > 0.05).
CONCLUSIONThe prolongation of Tp-e (> or = 120 ms) was associated with higher cardiac events in BrS patients.
