Risk factors related to mortality in old patients with coronary heart disease after revascularization.
- Author:
Xiao-hui LIU
1
;
Jun-ping KANG
;
Xin DU
;
Shao-ping NIE
;
Qiang LÜ
;
Jian-zeng DONG
;
Xin-min LIU
;
Xi-zhe ZHAO
;
Cheng-xiong GU
;
Fang-jiong HUANG
;
Shu-zheng LÜ
;
Fang CHEN
;
Yu-jie ZHOU
;
Chang-sheng MA
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Aged, 80 and over; Coronary Disease; mortality; surgery; Female; Follow-Up Studies; Humans; Male; Myocardial Revascularization; Postoperative Period; Prognosis; Regression Analysis; Risk Factors; Sex Factors; Survival Analysis
- From: Chinese Journal of Cardiology 2007;35(8):701-705
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the risk factors related to mortality in old patients with coronary heart disease after revascularization.
METHODSA total of 675 patients (498 males) with age >or= 70 years old who received revascularization during July 2003 to June 2004 and followed up > 30 days after discharge were included in this study. Clinical characteristics, death and major adverse cardiac and cerebral events (MACCE) during follow up were recorded.
RESULTSThe patients were followed up for a mean period of (754 +/- 355) days. 27 patients (4.0%) died and MACCE developed in 50 patients (7.4%) during follow up. Female and patients with anemia took a significantly higher risk of mortality (RR = 2.750, 95% CI 1.116 - 6.779, P = 0.028, RR = 0.385 95% CI 0.164 - 0.904, P = 0.028, respectively); Creatinine level is positively related to mortality rate. When comparing patients with Cr > 115 micromol/L and Cr > 177 micromol/L with patients with Cr < 115 micromol/L, the hazard rate was 2.963 and 10.785, respectively (95% CI 1.114 - 9.952, P = 0.035 and 95% CI 2.659 - 78.097, P = 0.000) after adjustment for other risk factors.
CONCLUSIONPreexisting anaemia (male Hb < 120 g/L, female Hb < 110 g/L), renal insufficiency (Cr > 115 micromol/L) and female gender were found to be independent risk factors for mortality in old patients with coronary heart disease post revascularization.