Diagnostic value of multidetector spiral computed tomography in identifying the composition of coronary atherosclerotic plaques.
- Author:
Ming-hui WANG
1
;
Jun-bo GE
;
Ke-qiang WANG
;
Zhi-qing LING
;
Ju-ying QIAN
;
Lei GE
;
Feng ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Atherosclerosis; diagnostic imaging; Coronary Angiography; Female; Humans; Male; Middle Aged; Tomography, Spiral Computed; methods; Ultrasonography, Interventional
- From: Chinese Journal of Cardiology 2007;35(8):727-730
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo estimate the feasibility of 16-multidetector spiral computed tomography (16-MDCT) on detecting coronary plaques in comparison with intravascular ultrasound (IVUS).
METHODSSixty-eight patients suspected of coronary heart diseases were examined by 16-MDCT, quantitative coronary angiography (QCA) and IVUS. Coronary stenosis was defined as lumen diameter reduction (DS) >or= 50%. Hounsfield units (HU) were used to determine different types of plaques: soft plaque (
RESULTSCompared to QCA, the sensitivity and the specificity for patients with DS >or= 50% were 91.8% (112/122) and 97.8% (556/568) respectively, the positive and negative predictive value were 90.3% (112/124) and 98.2% (556/566) respectively. In 96 plaques evaluated both by 16-MDCT and IVUS, 20 and 21 soft plaques, 37 and 36 fibrous plaques, 39 and 38 calcified plaques were identified by 16-MDCT and IVUS respectively. HU value of soft (11 +/- 36), fibrous (83 +/- 20), and calcified (292 +/- 80) plaques were significantly different (P < 0.05).
CONCLUSIONSNoninvasive 16-MDCT could correctly estimate coronary stenosis and coronary plaques compositions.
