Evaluation analysis of alkaloids in seed of Sophora flavescens from Shanxi province and exploration of its utilization value.
- Author:
Ze-Bin WENG
1
;
Jin-Ao DUAN
1
;
Sheng GUO
1
;
Zhen-Hua ZHU
1
;
Jun-Fei GU
1
;
Zhen-Hong LEI
2
;
An-Ping LI
3
Author Information
- Publication Type:Journal Article
- Keywords: Sophora alopecuroides; Sophora flavescens; alkaloids; resources utilization; seed
- From: China Journal of Chinese Materia Medica 2016;41(17):3265-3271
- CountryChina
- Language:Chinese
- Abstract: According to the research strategy of resource chemistry of Chinese medicinal materials and Chinese medicinal resources recycling utilization, this study intends to explore the potential resource-oriented utilization value of the seed of Sophora flavescens by contrasting with its kindred plant S. alopecuroides. This study established a rapid UPLC-Q-TOF-MS/MS and UPLC-TQ-MS/MS method to determine the alkaloids in the seed of S. flavescens. Results of UPLC-Q-TOF-MS/MS analysis showed that the alkaloids in the seed of S. flavescens were highly similar with S. alopecuroides.In the determination of 7 kinds of alkaloids, the total content was 11.203 and 15.506 mg•g⁻¹ in the seed of S. flavescens and S. alopecuroides, respectively. The content of oxymatrine, oxysophocarpine and sophoridine is high in the seed of S. flavescens. The results indicated that the seeds of S. flavescens. could be an important material resource to obtain alkaloids.