Construction of NIRS-based total quality control system for compound Ejiao oral liquid and relative thinking.

Author: Yan ZHANG ¹ ; Lu ZHANG ¹ ; Shou-Sheng TIAN ¹ ; Xiang-Shan ZHOU ¹ ; Wen-Long LI ² ; Hai-Bin QU ²
Author Information

1. Dong'e Ejiao Co., Ltd., Liaocheng 252201, China.
2. Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, China.
Publication Type:Journal Article
Keywords: compound Ejiao oral liquid; near infrared spectroscopy; process analytical technology; quality control
From: China Journal of Chinese Materia Medica 2016;41(19):3574-3578
CountryChina
Language:Chinese
Abstract: In this paper, near infrared spectroscopy (NIRS)-based total quality control system of compound Ejiao oral liquid is introduced briefly, including the quality control of raw traditional Chinese medicine (TCM) materials, monitoring and control of the extract and the alkaline precipitation technics, and also the inspection of finished products in both open bottle and non-opening modes. By analyzing and summing up the significance and difficulties, several important problems in the practical applications of NIRS technology are proposed, which will provide references for the similar studies of other TCM products.