Effect of shuxuetong in preventing restenosis after intracoronary stenting.
- Author:
Ai-hua LI
1
;
Kai-zheng GONG
;
Jun-feng YAN
;
Xiaoning SUN
;
Yiliang FENG
;
Zhengang ZHANG
Author Information
- Publication Type:Clinical Trial
- MeSH: Aged; Angioplasty, Balloon, Coronary; adverse effects; Coronary Disease; drug therapy; therapy; Coronary Restenosis; prevention & control; Drugs, Chinese Herbal; therapeutic use; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phytotherapy; Stents; adverse effects
- From: Chinese Journal of Integrated Traditional and Western Medicine 2004;24(10):879-881
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the effect of shuxuetong (SXT) in preventing restenosis after intracoronary stenting.
METHODSSixty-eight patients, accepted intracoronary stenting, were divided into two groups, the SXT group and the control group, both of them were treated with conventional treatment, and to the SXT group, SXT was given additionally. The condition of treated coronary artery restenosis in the two groups was compared by way of quantitative coronary angiography and a 6-month follow-up study was adopted.
RESULTSFollow-up study was completed in 43 patients (23 cases in the SXT group, and 20 in the control group). The angina recurrence rate in the SXT group (3 cases, 13%) was significantly lower than that in the control group (7 cases, 35%, P < 0.05). Quantitative coronary angiography showed the restenosis degree of operated artery in the SXT group was significantly milder than that in the control group, with the last lumen losing and index in the SXT group (0.46 +/- 0.25 mm, 24.26 +/- 8.64%) less than those in the control group (0.75 +/- 0.33 mm, 31.25 +/- 11.03%). The net gain lumen and the net gain index in the SXT group (1.23 +/- 0.30 mm, 58.96 +/- 24.68%) were greater than those in the control group (0.98 +/- 0.33 mm, 42.68 +/- 29.51%), all P < 0.05. But the restenosis rate in the two groups was insignificantly different (P > 0.05).
CONCLUSIONSXT might has some definite effect in preventing restenosis after intracoronary stenting.
