Agreements between Indirect Calorimetry and Prediction Equations of Resting Energy Expenditure in End-Stage Renal Disease Patients on Continuous Ambulatory Peritoneal Dialysis.
10.3349/ymj.2008.49.2.255
- Author:
Seoung Woo LEE
1
;
Hyo Jung KIM
;
Hei Kyung KWON
;
Sook Mee SON
;
Joon Ho SONG
;
Moon Jae KIM
Author Information
1. Division of Nephrology and Hypertension, Department of Internal Medicine, Kidney Disease Research Group, Inha University College of Medicine, Incheon, Korea. nhkimj@inha.ac.kr
- Publication Type:Original Article
- Keywords:
Energy metabolism;
chronic kidney failure;
continuous ambulatory peritoneal dialysis
- MeSH:
Adolescent;
Adult;
Calorimetry, Indirect/*methods;
*Energy Metabolism;
Female;
Humans;
Kidney Failure, Chronic/metabolism/*therapy;
Male;
Middle Aged;
Models, Biological;
Peritoneal Dialysis, Continuous Ambulatory/*methods
- From:Yonsei Medical Journal
2008;49(2):255-264
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Equations are frequently used to estimate resting energy expenditure (REE) in a clinical setting. However, few studies have examined their accuracy in end-stage renal disease (ESRD) patients. PATIENTS AND METHODS: To investigate agreement between indirect calorimetry and several REE estimating equations in 38 ESRD patients on peritoneal dialysis, we performed indirect calorimetry and compared the results with REEs estimated using 5 equations [Harris-Benedict (HBE), Mifflin, WHO, Schofield, and Cunningham]. RESULTS: Measured REE was 1393.2 +/- 238.7kcal/day. There were no significant differences between measured and estimated REEs except Mifflin (1264.9 +/- 224.8kcal/day). Root mean square errors were smallest for HBE, followed by Schofield, Cunningham, and WHO, and largest for Mifflin (171.3, 171.9, 174.6, 175.3, and 224.6, respectively). In Bland-Altman plot, correlation coefficients between mean values and differences were significant for HBE (r=0.412, p=0.012) and tended to be significant for Cunningham (r=0.283, p=0.086). In DM patients and patients with overhydration, HBE showed significant underestimation when REE increased. CONCLUSION: In ESRD patients on continuous ambulatory peritoneal dialysis (CAPD), REE-estimating equations have no significant differences from indirect calorimetry, except Mifflin. However, HBE showed greater bias than others when REE was high.
