Outcome Following Surgical Closure of Patent Ductus Arteriosus in Very Low Birth Weight Infants in Neonatal Intensive Care Unit.
10.3349/ymj.2008.49.2.265
- Author:
Ga Yeun LEE
1
;
Young Bae SOHN
;
Myo Jing KIM
;
Ga Won JEON
;
Jae Won SHIM
;
Yun Sil CHANG
;
June HUH
;
I Seok KANG
;
Ji Hyuk YANG
;
Tae Gook JUN
;
Pyo Won PARK
;
Won Soon PARK
;
Heung Jae LEE
Author Information
1. Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. wonspark@skku.edu
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Patent ductus arteriosus;
ligation;
neonatal intensive care unit;
very low birth weight infants
- MeSH:
Ductus Arteriosus, Patent/*surgery;
Humans;
Infant, Newborn;
*Infant, Very Low Birth Weight;
Intensive Care Units, Neonatal/*statistics & numerical data;
Ligation/*methods;
Treatment Outcome
- From:Yonsei Medical Journal
2008;49(2):265-271
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The aims of this study were to determine the factors affecting the outcome of patent ductus arteriosus ligation in very low birth weight infants (VLBWI) and demonstrate the safety of PDA ligation in VLBWI performed in the neonatal intensive care unit (NICU). MATERIALS AND METHODS: From October 1994 to July 2006, medical records of 94 VLBWI weighing < 1,500g who underwent PDA ligation in the NICU of Samsung Medical Center were reviewed retrospectively. Factors affecting the final outcome of PDA ligation were evaluated by dividing the infants into 3 groups according to mortality and major morbidities as follows: mortality group (Mo), major morbidity group (Mb), and no major morbidity group (NM). RESULTS: In the Mo group, birth weight was significantly lower and the preoperative mean FiO(2) and mean dopamine dose were significantly higher than those in the other 2 groups. There was no significant difference in gestational age, incidence of RDS, number of courses of indomethacin, surgery-related factors, including weight and age at surgery, perioperative vital signs, and complications after surgery between the 3 groups. During surgery in the NICU, there were no significant hemodynamic instability or serious acute complications. CONCLUSION: The factors affecting the outcome of surgery in VLBWI are not the factors related to surgery but the preoperative conditions related to the underlying prematurity. PDA ligation of VLBWI performed in the NICU is safe without serious complications.
