Acute Human Immunodeficiency Virus Syndrome Presenting with Hemophagocytic Lymphohistiocytosis.
10.3349/ymj.2008.49.2.325
- Author:
Kyung Hwa PARK
1
;
Ho Sung YU
;
Sook In JUNG
;
Dong Hyeon SHIN
;
Jong Hee SHIN
Author Information
1. Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea. sijung@chonnam.ac.kr
- Publication Type:Case Report ; Research Support, Non-U.S. Gov't
- Keywords:
Acute human immunodeficiency virus syndrome;
hemophagocytic lymphohistiocytosis
- MeSH:
Acquired Immunodeficiency Syndrome/complications/*diagnosis;
Adult;
Diagnosis, Differential;
HIV Infections/complications/*diagnosis;
Humans;
Korea;
Lymphohistiocytosis, Hemophagocytic/etiology/*pathology;
Male
- From:Yonsei Medical Journal
2008;49(2):325-328
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hemophagocytic lymphohistiocytosis (HLH) has been described in patients with advanced stages of human immunodeficiency virus (HIV) infection, but rarely occurs during the seroconversion stage of acute HIV infection. We report a case of acute HIV syndrome that presented with virus-associated HLH. The patient recovered spontaneously without any immunomodulating therapy. This case suggests that acute HIV infection should be included in the differential diagnosis of HLH and indicates that HLH associated with acute HIV infection can have a favorable outcome.