Diagnosis of obstructive coronary artery disease using CT coronary angiography combined with CT first-pass myocardial perfusion imaging at rest.
- Author:
Qi WANG
1
;
Jing QIN
;
Luyue GAI
;
Zhiguo WANG
;
Zhiwei GUAN
;
Zhijun SUN
;
Wei DONG
;
Li YANG
;
Yundai CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Coronary Angiography; Coronary Artery Disease; diagnostic imaging; Feasibility Studies; Female; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Predictive Value of Tests; Sensitivity and Specificity; Tomography, Spiral Computed
- From: Journal of Southern Medical University 2013;33(6):819-825
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo assess the feasibility and accuracy of CT coronary angiography (CTCA) combined with CT first-pass myocardial perfusion imaging (CT first-pass MPI) at rest for diagnosis of obstructive coronary artery disease (CAD).
METHODSFifty-five patients, suspected or diagnosed as CAD, were performed with CTCA and CAG within 2 weeks. CT first-pass MPI detected myocardial ischemia through analyzing the raw date of CTCA.
RESULTSComparison with the results of CAG, the sensibility, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of CT first-pass MPI at rest for detecting obstructive CAD were 84.6%, 68.8%, 86.8%, 64.7% and 80.0%, respectively; and 92.3%, 93.8%, 97.3%, 83.3%, 92.7% for CTCA combined with CT first-pass MPI, respectively.
CONCLUSIONCTCA combined with CT first-pass MPI at rest could detect obstructive CAD feasible and accurately.
