Behcet's disease complicated by malignant lymphoma: a case report and literature review.
- Author:
Qin HUANG
1
;
Weinan LAI
;
Min YANG
Author Information
1. Department of Rheumatology and Immunology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. qinzihq@foxmail.com
- Publication Type:Case Reports
- MeSH:
Adult;
Behcet Syndrome;
complications;
Humans;
Lymphoma, Extranodal NK-T-Cell;
complications;
Male
- From:
Journal of Southern Medical University
2013;33(6):934-936
- CountryChina
- Language:Chinese
-
Abstract:
Malignant lymphoma complicated by Behcet's disease (BD) is a rare clinical entity. We report a case of BD complicated by malignant lymphoma in a 26-year-old male patient. The patient was diagnosed to have terminal ileum extranodal NK/T-cell lymphoma (nasal type) during treatment for BD with cyclophosphamide (CTX), immunoregulants and biological agents. This is the first case reported in China and the second case globally. The pathogenesis of BD complicated by malignant lymphoma remains unclear. We reviewed the relevant literatures to summarize the clinical characteristics of BD complicated by extranodal NK/T-cell lymphoma (nasal type) and discuss the possible pathogenesis in light of immunology, EB virus infection and medications.
