Experimental study on pulp revitalization of Beagle dog′s immature permanent teeth after pulpectomy
10.3760/cma.j.issn.1002-0098.2011.08.011
- VernacularTitle:去髓年轻恒牙牙髓组织再生的动物实验
- Author:
Jian-Zhen YANG
1
;
Yong OUYANG
;
Zhi-Qing LIAO
Author Information
1. 南方医科大学附属口腔医院(广东省口腔医院)
- Keywords:
Animals,laboratory;
Dental pulp;
Regeneration;
Neovascularization,physiologic
- From:
Chinese Journal of Stomatology
2011;46(8):489-493
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the process of pulp revitalization of immature permanent teeth after pulpectomy. Methods Thirty-two single-rooted teeth with open apices from 4 Beagle dogs aged 4 months were included in the study. The pulpal tissues of 8 front teeth with single root of each dog were removed, and a blood clot was produced to the level of the cementoenamel junction followed by a double seal of mineral trioxide aggregate and composite resin. At day 7, 14, 21 and 28, respectively after operation, the dog was sacrificed, and then longitudinal paraffin sections were made for histologic investigation. ResultsAfter 7 days, about one thirth of the pulp chamber had an ingrowth of new tissue. After 14, 21, 28 days, there were more and more new tissue in the chamber. This new tissue consisted of well-organized and well-vascularized connective tissue. Hard tissue was too observed in the root canal. In some cases, the newly generated hard tissue even deposited against the canal dentinal walls. Conclusions The pulp of immature permanent teeth can revitalize after removal of the original pulp tissue under suitable conditions.
