Primary pigmented nodular adrenocortical disease report of 5 cases.
- Author:
Yu ZHU
1
;
Yu-xuan WU
;
Wen-bin RUI
;
Ding-yi LIU
;
Wen-long ZHOU
;
Rong-ming ZHANG
;
Fu-kang SUN
;
Chong-yu ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adrenalectomy; Adult; Child; Cushing Syndrome; diagnosis; pathology; surgery; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Pituitary-Adrenal Function Tests; Retrospective Studies; Tomography, X-Ray Computed
- From: Chinese Journal of Surgery 2005;43(14):944-947
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the pathology, diagnostic and therapeutic method of primary pigmented nodular adrenocortical disease (PPNAD).
METHODSThe data of 5 cases of PPNAD were analyzed retrospectively. Among the 5 cases, 2 were male and 3 were female. The range of age was from 12 to 53 years. All the 5 cases had symptoms of Cushing syndrome. The diagnose depended on the results of endocrine exams, ultrasound, CT, MR and pathological reports. All patients received operation of unilateral adrenalectomy. The therapeutic effects were determined by post-operative results, which concluded clinical symptoms and endocrine exams.
RESULTSThe follow-up time was from 4 months to 3 years. All patients' symptoms of Cushing syndrome were relieved in 6 months after operation. The endocrine exam was normal in one case and obvious improved in the other four cases. Up to now, one patient drop out of the follow-up, the other 4 cases had no evidence of recurrence.
CONCLUSIONPPNAD is a rare type of Cushing syndrome. Diagnose depends on endocrine exams and pathological results. Operation is the effective method for the disease.
