Follow-up study in endovascular therapy for the renal artery stenosis.
- Author:
Ke-qin WANG
1
;
Chao YUAN
;
Wang-de ZHANG
;
Biao YUAN
;
Tong XING
;
Tan LI
;
Yang ZHANG
;
Sheng-han SONG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon; methods; Female; Follow-Up Studies; Humans; Hypertension, Renovascular; etiology; Male; Middle Aged; Renal Artery Obstruction; complications; therapy; Renal Insufficiency; etiology; Stents; Treatment Outcome
- From: Chinese Journal of Surgery 2005;43(19):1268-1270
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the safety and efficacy of endovascular therapy for renal artery stenosis.
METHODSPercutaneous transluminal renal angioplasty with stent (PTRAS) was performed on 33 consecutive patients with severe renal artery stenosis who suffered from poorly controlled hypertension or renal dysfunction. They were subsequently underwent 7 to 49 months clinical follow up for the effect of the procedure on renal function, blood pressure control, mortality.
RESULTSAngiographic success was obtained in 32 (97.0%) of the 33 patients. The mortality was 18.2%. After PTRAS, two (6.1%) died of myocardial infarction within 4 months. Four (12.1%) patients with preoperative serum creatinine (Scr) > or = 177 micromol/L died of uraemia within 17 approximately 28 months. Twelve and twenty-four months after the procedure, systolic and diastolic blood pressure of 26 (78.8%) cases with preoperative Scr < 177 micromol/L significantly decreased (P < 0.05), with less antihypertensive medications taken and satisfactory renal function.
CONCLUSIONFor patients without serious cardiorenal disease, PTRAS has a beneficial effect on blood pressure and renal function. For patients with serious cardiorenal disease or preoperative Scr > or = 177 micromol/L, the mortality is higher. PTRAS should be performed prudently. The preservation of renal function may be enhance by using renal protection device.