Experimental study on the osseointegration of nanophase hydroxyapatite biograde-coated implants.
- Author:
Yi WANG
1
;
Yan-bin TAN
;
Qing-ming YANG
;
Lian-fu DENG
;
Shao-xian ZENG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Bone Substitutes; chemistry; Coated Materials, Biocompatible; chemistry; Dogs; Durapatite; chemistry; Male; Materials Testing; Nanoparticles; Osseointegration; physiology; Surface Properties
- From: Chinese Journal of Surgery 2005;43(20):1336-1339
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the osseointegration of the nanophase hydroxyapatite biograde-coated implants and host bone.
METHODSNanophase hydroxyapatite biograde-coated implants, hydroxyapatite biograde-coated implants and noncoated Ti-6Al-4V implants were inserted into both femoral of Beagle canines the tissue response, dynamic osteogensis and SEM were studied at 4, 8 and 12 weeks.
RESULTSThe degradation of nanophase hydroxyapatite was slower than hydroxyapatite, dynamic osteogensis and the form of osteoblast were better than the control groups.
CONCLUSIONThe biological reaction of Nanophase hydroxyapatite biograde-coated implants is better than hydroxyapatite coated implant.