Diagnosis and treatment of cytomegalovirus pneumonia after liver transplantation.
- Author:
Gen-shu WANG
1
;
Hua LI
;
Gui-hua CHEN
;
Min-qiang LU
;
Yang YANG
;
Chang-jie CAI
;
Chi XU
;
Shu-hong YI
;
Hui-min YI
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Combined Modality Therapy; Cytomegalovirus Infections; diagnosis; etiology; therapy; Humans; Liver Transplantation; adverse effects; Male; Middle Aged; Pneumonia, Viral; diagnosis; etiology; therapy; Postoperative Complications; therapy; Retrospective Studies; Treatment Outcome
- From: Chinese Journal of Surgery 2005;43(23):1512-1515
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVESTo investigate the diagnosis and treatment of cytomegalovirus (CMV) pneumonia after liver transplantation.
METHODSFive cases of CMV pneumonia after liver transplantation were analyzed retrospectively. CMV pneumonia was diagnosed according to its clinical manifestation, chest X-ray, and etiologic test. All 5 patients received comprehensive therapy based on anti-virus treatment and immunologic adjustment.
RESULTSThe clinical manifestation of CMV pneumonia after liver transplantation was nonspecific. Its main symptoms included fever, cough, dyspnea, tachycardia, fatigue, hypoxemia and neutropenia. The chest X-ray showed interstitial pneumonia. Sera CMV antigens or antibodies could be detected in the patients. Four patients were cured and 1 patient died.
CONCLUSIONSThe clinical manifestation of CMV pneumonia was nonspecific. CMV pneumonia could be diagnosed according to its manifestations, chest X-ray and etiologic test. The comprehensive therapy based on anti-virus treatment and immunologic adjustment was effective for the disease.