Smoking impairs endothelial function in ED patients.
- Author:
Feng-juan YAO
1
;
Yan-ping HUANG
;
Hong LIN
;
Dong-hong LIU
;
Rui FAN
;
Yan-qiu LIU
;
Kun LU
;
Chun-hua DENG
;
Xiang-zhou SUN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Case-Control Studies; Endothelium, Vascular; physiopathology; Erectile Dysfunction; physiopathology; Humans; Impotence, Vasculogenic; physiopathology; Male; Smoking; Vasodilation
- From: National Journal of Andrology 2011;17(5):414-417
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo determine whether smoking affects the endothelial function of young ED patients with no cardiovascular disease.
METHODSThis study included 69 ED patients (21 smokers and 48 non-smokers) and 16 age-matched normal healthy controls. All underwent measurement of brachial artery flow-mediated vasodilation (FMD) and examinations of blood pressure, cholesterol, triglycerides and glucose.
RESULTSBrachial artery FMD was remarkably decreased in the ED patients, even more significantly in the smokers ([6.0 +/- 0.8]%) than in the non-smokers ([9.7 +/- 2.5]%) (P < 0.05), as compared with that in the normal healthy controls ([14.0 +/- 2. 5]%, P < 0.05).
CONCLUSIONEndothelial function is impaired in ED patients, and is further damaged by smoking.
