Surgical Outcome of Intraoperative Episcleral Application of 5-Fluorouracil in Primary Trabeculectomy.
- Author:
Jong Gyoo YANG
1
;
Changwon KEE
Author Information
1. Department of Ophthalmology, Colleg of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
5-fluorouracil;
trabeculectomy;
uncomplicated glaucoma
- MeSH:
Blister;
Fluorouracil*;
Follow-Up Studies;
Glaucoma;
Hyphema;
Porifera;
Trabeculectomy*
- From:Journal of the Korean Ophthalmological Society
1997;38(9):1641-1646
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We analyzed the outcome of primary trabeculectomy performed with intraoperative 5-fluorouracil(5-FU) sponge application on episclera and under lamella scleral flap in seventeen uncomplicated glaucoma eyes. The mean preoperative intraocular pressure(IOP) was 36.8+/-11.0mmHg. The mean postoperative IOP was 14.2+/-3.5mmHg after mean follow-up of 11.4 months. Two eyes required additional anti-glaucoma medications. Compliations included chronic hypotony(1 eye), shallow anterior chamber(2 eyes), and hyphema (1 eye). No eye showed corneal problems, hypotonic maculopathy, and bleb leakage. This study suggests that a single intraoperative use of 5-FU in primary trabeculectomy is an effective way of improving IOP control and of decreasing complications in eyes with uncomplicated glaucoma.
