Significance of blood HCV RNA screening in the prevention of post-transfusion hepatitis C.
- Author:
Ying ZHANG
1
;
Jing LI
;
Yu-feng LIU
;
Hong-wei ZHAO
;
Geng-shan TIAN
Author Information
- Publication Type:Journal Article
- MeSH: Feasibility Studies; Follow-Up Studies; Hepacivirus; genetics; Hepatitis C; blood; etiology; prevention & control; Humans; Mass Screening; methods; RNA, Viral; blood; genetics; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Transfusion Reaction
- From: Chinese Journal of Experimental and Clinical Virology 2006;20(1):70-72
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUNDTo investigate the significance of blood HCV RNA screening in the prevention of post-transfusion hepatitis C.
METHODSTotally 56,400 anti-HCV negative blood samples collected from Jan. 2000 to Dec. 2003 were tested for HCV RNA by RT-PCR, and the patients who received the HCV RNA negative blood were followed up.
RESULTSThe HCV RNA positive rate was 2.5 per thousand (146/56,000) and none of the patients followed up suffered from HCV infection.
CONCLUSIONHCV RNA screening for the anti-HCV negative blood samples is very effective and feasible for prevention of post-transfusion hepatitis C.
