Comparative evaluation of Hebei HIV-1 p24 kit for the detection of human immunodeficiency virus.
- Author:
Yi-shu YANG
1
;
Run-tian WANG
;
Xiao-guang ZHANG
;
Hong-zhong ZHANG
;
Hui-fen WANG
;
Ze-lin LI
;
Yi ZENG
Author Information
- Publication Type:Journal Article
- MeSH: Anti-HIV Agents; isolation & purification; pharmacology; Cell Line; Drug Evaluation, Preclinical; instrumentation; methods; Feasibility Studies; HIV Core Protein p24; analysis; HIV-1; drug effects; growth & development; immunology; Humans; Reagent Kits, Diagnostic; standards; Reproducibility of Results
- From: Chinese Journal of Experimental and Clinical Virology 2007;21(1):8-10
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo probe into the feasibility of screening anti-HIV compounds by using HIV-1 p24 detection kit made by Hebei Medical University.
METHODSThe sensitivity, reproducibility and efficacy of the Hebei p24 kit were evaluated compared with the commercially available Vironostika HIV-1 Antigen Microelisa System (Biomerieux).
RESULTSHebei p24 kit had high sensitivity and good reproducibility. In vitro screening demonstrated that there was no statistically significant difference (P greater than 0.05) between these two kits in assessing anti-HIV compounds.
CONCLUSIONHebei p24 kit could be used as an easily affordable alternative method for detection of HIV-1 in screening anti-HIV compounds.
