Hepatitis E virus infection in population of non-remunerate blood donors in Shaoxing.
- Author:
Lie-yong SANG
1
;
Pei-fen ZHUANG
;
Li-qiang FU
;
Yi LIU
;
Sheng-xiang GE
;
Jun ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Age Factors; Blood Donors; China; epidemiology; Enzyme-Linked Immunosorbent Assay; Female; Hepatitis E; blood; epidemiology; virology; Hepatitis E virus; classification; genetics; immunology; Humans; Immunoglobulin G; blood; Immunoglobulin M; blood; Male; Middle Aged; Phylogeny; RNA, Viral; blood; genetics; Reverse Transcriptase Polymerase Chain Reaction; Young Adult
- From: Chinese Journal of Experimental and Clinical Virology 2007;21(1):29-31
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the incidence of HEV infection in population of non-remunerate blood donors in Shaoxing.
METHODSBlood specimens from 3701 non-remunerate blood donors were collected, ELISA were used to study anti-HEV IgG and IgM antibodies, RT-PCR were further used to study HEV RNA in samples from donors whose anti-HEV IgM was positive.
RESULTSAnti-HEV IgG positive rate was 29.19% (1107/3701), anti-HEV IgM positive rate was 1.35% (50/3701) among non-remunerate blood donors in Shaoxin. Six cases were positive for HEV RNA. The positive rate was 0.16% (6/3701), and all the 6 cases belonged to HEV genotype 1. Different seasons showed no interference on the positive rate of IgG and IgM.
CONCLUSIONThe detecting and studying of HEV infection among donors was important to ensure the safety of blood products and blood transfusion.
