Combination therapy of cyclosporine and prednisolone in a dog with systemic lupus erythematosus.
10.14405/kjvr.2016.56.1.47
- Author:
Yeon Hee KIM
1
;
Min Hee KANG
;
Hee Myung PARK
Author Information
1. Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea. parkhee@konkuk.ac.kr
- Publication Type:Case Report
- Keywords:
antinuclear antibody;
cyclosporine;
glomerulonephritis;
polyarthritis;
systemic lupus erythematosus
- MeSH:
Animals;
Antibodies, Antinuclear;
Arthritis;
Child;
Cyclosporine*;
Dogs*;
Female;
Fever;
Glomerulonephritis;
Humans;
Lupus Erythematosus, Systemic*;
Neutrophils;
Physical Examination;
Prednisolone*;
Proteinuria;
Synovial Fluid;
Urinalysis;
Viscosity
- From:Korean Journal of Veterinary Research
2016;56(1):47-49
- CountryRepublic of Korea
- Language:English
-
Abstract:
An 11-year-old, spayed female poodle presented with fever and shifting lameness. Physical examination revealed hyperthermia (40.6℃), and proteinuria was detected upon urinalysis. Increased neutrophils (83%) and decreased viscosity were revealed upon synovial fluid analysis. Serum antinuclear antibody was positive at 1 : 80. Based on these findings, the dog was diagnosed with systemic lupus erythematosus. Immunosuppressive therapy was initiated with prednisolone and cyclosporine, and the condition was markedly improved after the treatments. This case report describes the clinical and laboratory findings, imaging characteristics and successful outcomes after prednisolone plus cyclosporine therapy in a canine systemic lupus erythematosus case.
