The Heart Rate Response to Intravenous Atropine during Propofol or Enflurane Anesthesia.
10.4097/kjae.2005.49.4.455
- Author:
Su Sang JUNG
1
;
Ji Sung KIM
;
Keon Sik KIM
;
Ok Young SHIN
;
Wha Ja KANG
Author Information
1. Department of Anesthesiology and Pain Medicine, Bupyung Serim Hospital, Incheon, Korea.
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
atropine;
bradycardia;
enflurane;
heart rate;
propofol
- MeSH:
Anesthesia*;
Anesthesia, General;
Anesthetics;
Atropine*;
Blood Pressure;
Bradycardia;
Enflurane*;
Heart Rate*;
Heart*;
Humans;
Hysterectomy;
Midazolam;
Propofol*
- From:Korean Journal of Anesthesiology
2005;49(4):455-460
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Propofol increases the risk of bradycardia compared with other anesthetics. This paper reports the heart rate response to intravenous atropine during propofol and enflurane anesthesia. METHODS: Sixty patients undergoing a transabdominal hysterectomy under general anesthesia were randomly assigned to two groups: the propofol group and the enflurane group. All the patients received midazolam 2 mg intramuscularly and were then anesthetized with propofol or enflurane. The blood pressure and heart rate were taken at 1 min intervals for 10 min after a bolus injection of atropine 5microgram/kg. RESULTS: In the enflurane group, the systolic blood pressure and heart rate were increased significantly at 1, 2 and 3 min after the atropine injection (P<0.05). When the two groups were compared, the heart rate in the enflurane group was significantly higher at 1, 2 and 3 min after atropine injection than in the propofol group (P<0.05). CONCLUSIONS: The heart rate response to intravenous atropine during propofol anesthesia is attenuated compared with enflurane anesthesia.
