Serological survys on anti-H1N1 IgG of blood donors in Dongguan

VernacularTitle:东莞市无偿献血者甲型H1N1流感抗体血清学调查
Author: De-Wen WANG ¹ ; Fu-Ping LIU ; Bing LIANG
Author Information

1. 广东省东莞市中心血站
Keywords: Influenza A virus,human; Blood donors; Influenza vaccine; Immunity,active
From: Chinese Journal of Experimental and Clinical Virology 2012;26(4):263-265
CountryChina
Language:Chinese
Abstract: Objective To access the sustained immune effect in influenza A H1N1 vaccine vaccinated-blood donors as well as the level of anti-H1N1 IgG in unvaccinated-blood donors in order to provide reference for preventing and treating influenza A H1N1.Methods Anti-H1N1 IgG was detected in 1166 vaccinated-blood donors as well as 1265 unvaccinated-blood donors by ELISA method in Dongguan from January 2010 to June 2010.Results The mean positive rate and high-titer rate of anti-H1N1 IgG were 78.82％ and 46.57％ respectively,both of which were sustained at relatively high level after reaching their peak at vaccination time of 71-90 d.The mean positive rate of anti-H1N1 IgG in unvaccinated-blood donors was 26.01％.No difference was found in the positive rate of anti-H1N1 IgG among different gender or age groups( P ＞0.05).Conclusion The influenza A H1N1 vaccine,with good sustained immune effect,plays an important role in preventing and treating influenza A H1N1.The positive rate of anti-H1N1 IgG in influenza A H1N1 vaccine unvaccinated-blood donors is low.Vaccination should be strengthened.