Research of the relationship between cervical cytology and HPV test and lesions in the cervical tissue
10.3760/cma.j.issn.1003-9279.2012.04.011
- VernacularTitle:宫颈细胞学筛查及高危型HPV检测与宫颈组织学改变的相关性研究
- Author:
Li-Dong ZHANG
1
;
Wei XIE
;
Jing PEI
;
Dan ZHAO
Author Information
1. 广州医学院附属第三医院
- Keywords:
Cytology;
Papillomavirus,human;
Pathology
- From:
Chinese Journal of Experimental and Clinical Virology
2012;26(4):276-278
- CountryChina
- Language:Chinese
-
Abstract:
Objective Discussion of the relationship between cervical cytology and high-risk HPV test and lesions in the cervical tissue.Method The 254 infertile patients were graded into 4 groups based on the results of cervical cytology and high-risk HPV test.The patients in group A were the cervical cytology -positive and HPV-positive.The cervical cytology -positive and HPV-negative patients were in group B.The cervical cytology -negative and HPV-positive patients were in group C and cervical cytology -negative and HPV-negative in group D.Retrospective analysis was used in the relationship between the results and lesions in the cervical tissue.Results The incidence of CIN Ⅱ and higher grade than CIN II was significant higher in group A than in group B (P <0.01).The incidence ofCIN Ⅰ was no difference among A,B and C group ( P >0.05).The sensitivity was 100.0% and the specificity was 46.74% when cervical cytology was used to test the CIN Ⅱ grade.But the sensitivity changed to 97.22% and the specificity 87.16% when both of the cervical cytology and HPV test were used.Conclusion The cervical cytology is the first choice in cervical examination.And the accuracy will significant higher when the HPV test is used simultaneously.