Clinical analysis of 134 cases of HEV-related liver failure
10.3760/cma.j.issn.1003-9279.2012.04.019
- VernacularTitle:134例HEV相关肝衰竭患者临床特点分析
- Author:
Bing ZHU
1
;
Shao-Li YOU
;
Hong ZANG
;
Yi-Hui RONG
;
Ai-Min ZHANG
;
Chen LI
;
Jing CHEN
;
Hong-Ling LIU
;
Zhi-Hong WAN
;
Shao-Jie XIN
Author Information
1. 解放军第302医院
- Keywords:
Liver failure;
Hepatitis E;
Clinical medicine
- From:
Chinese Journal of Experimental and Clinical Virology
2012;26(4):301-303
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical features of hepatitis E virus-related liver failure.Methods 134 patients with HEV-related liver failure were analyzed retrospectively.Results HEV-related liver failure accounted for 8.45 percent of the total number of hepatitis E patients in the hospital.Of the 134 patients,68 were infected with simple HEV,66 had the superinfection with HBV.The average age of simple HEV-related liver failure patients (56.12 ± 14.29) was higher than that of HBV superinfectiong liver failure patients(P ＜0.05).The ratio of elderly patients ( ≥60 years) in simple HEV-related liver failure patients (45.59％) was significantly higher than that of the other group( 13.64％,P ＜ 0.05 ).The ratio of direct bilirubin/total bilirubing ( 0.72 ± 0.07,0.69 ± 0.08 ),and serum alanine aminotransferase [ ( 1250.90 ± 1593.97) U/L,(616.26 ± 797.62 ) U/L]were significantly higher in simple HEV-related liver failure patients than in HBV superinfectiong liver failure patients ( P ＜ 0.05 ),but the total bilirubing had no significant difference (P ＞0.05).The disease outcome and stage were no-significant difference in the two groups(P ＞ 0.05).Conclusion Simple HEV-related liver failure patients may have older age,higher aminotransferase,higher ratio of direct bilirubin/total bilirubin,but disease outcome and stage were nosignificant difference in the two groups.
