Analysis of the related risk factors of diabetic peripheral neuropathy.
- Author:
Chen NIE
1
;
Hai-Ping BAO
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Blood Glucose; metabolism; Body Mass Index; C-Peptide; blood; China; Diabetes Mellitus, Type 2; complications; Diabetic Neuropathies; blood; epidemiology; etiology; Female; Glycated Hemoglobin A; metabolism; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; blood; epidemiology; etiology; Risk Factors
- From: Chinese Journal of Experimental and Clinical Virology 2012;26(6):467-469
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the risk factors of diabetic peripheral neuropathy (DPN) and the relationship between DPN and diabetic retinopathy (DR).
METHODSThe data of the in-patients with type 2 diabetes mellitus (T2 DM) were retrospectively studied. A total of 200 T2 DM patients were divided into DPN group (n = 136) and non-DPN group (n = 64) according to peripheral neuropathy. The basic clinical data and the incidence rate of DR were compared between two groups. Logistic regression analysis was used to study the risk factors of DPN.
RESULTSThe course of disease, the level of BMI, glycosylated hemoglobin (HbA1c), 2 hour postprandial blood glucose (2 hPG), 2 hour glucose C peptide (2 hC-P) and the incidence rate of the DR were significantly different between two groups (P < 0.01). Logistic regression analysis showed that significant differences were observed in T2 DM complicated by DR (P = 0.023), the course of disease (P = 0.008), the level of HbA1c (P = 0.006), BMI (P = 0.000) and 2 hC-P (P = 0.065).
CONCLUSIONDiabetic retinopathy, the course of disease, the level of BMI,HbA1c and 2 hC-P are the risk factors for type 2 diabetic peripheral neuropathy. Diabetic peripheral neuropathy is positive correlated with diabetic retinopathy.
