Analysis on genetic characteristics of mumps virus strains circulating in Hunan province in 2011.
- Author:
Fang-Cai LI
1
;
Ai-Li CUI
;
Hong ZHANG
;
Li DENG
;
Xing-Yu XIANG
;
Yi-Wei HUANG
;
Wei-Chao LI
;
Yun-zhi LIU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Cercopithecus aethiops; China; epidemiology; Genetic Variation; Genotype; Humans; Mumps; epidemiology; virology; Mumps virus; genetics; isolation & purification; Phylogeny; Vero Cells; Viral Proteins; genetics
- From: Chinese Journal of Experimental and Clinical Virology 2013;27(1):25-27
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo be acquainted with genetic characteristics and variation of mumps virus strains circulating in Hunan province.
METHODSMumps virus (MV) strains were isolated using Vero/ SLAM cells. The small hydrophobic protein (SH) genes of MV isolates were sequenced, and the sequences were analysed phylogenetically between the isolated strains and other reference mumps strains.
RESULTS4 mumps virus strains were isolated from 16 specimens collected in 2011 from different regions of Hunan province. The genotype of isolated strains were supposed to be F type.
CONCLUSIONGenotype F is the main genotype of circulating strains in Hunan province in 2011 and there is no variation between genotype.
