Research progress of structures and pharmacological activities of phthalides from Angelica sinensis.

Author: Jie-Li LV ¹ ; Hong-Li CHEN ¹ ; Jin-Ao DUAN ² ; Jun-Wei LIU ¹
Author Information

1. School of Pharmacy, Xinxiang Medical University, Xinxiang 453003, China.
2. Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Publication Type:Journal Article
Keywords: Angelica sinensis; chemical structure; pharmacological activity; phthalide
From: China Journal of Chinese Materia Medica 2016;41(2):167-176
CountryChina
Language:Chinese
Abstract: Angelica sinensis(Umbelliferae)is a worldwide-known medicinal plant and also a famous traditional Chinese medicinal herb. It is recorded to possess the efficacy of enriching the blood and invigorating the circulation of blood of the individual.Danggui was extensively applied to the treatment of gynecological disorders. Modern researches indicate that phthalides are main chemical components related to the bioactivities of A.sinensis, such as anti-tumor, analgesic and neuroprotective effect.The advances in studies on the structures and pharmacological activities of phthalides from A.sinensis are reviewed to provide references for further researches and utilization of their medicinal value.