The Effects of Inline Intravenous Filtration on Bacteria, Candida and Bacterial Endotoxin Retentions.
- Author:
Min Seung KANG
1
;
Kwang Hee KIM
;
Heung Jung WOO
;
Chae Seung LIM
;
Young Ki KIM
;
Kap No LEE
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Intravenous filter;
Bacteria;
Endotoxin
- MeSH:
Administration, Intravenous;
Bacteria*;
Candida*;
Culture Media;
Filtration*;
Horseshoe Crabs;
Pseudomonas aeruginosa;
Staphylococcus epidermidis
- From:Korean Journal of Infectious Diseases
1999;31(2):136-140
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: In-line intravenous filters have been used in intravenous administration sets of fluid to retain bacteria and bacterial endotoxin. We evaluated the effects of intravenous filters on Staphylococcus epidermidis, Pseudomonas aeruginosa, Candida and bacterial endotoxin retention. METHODS: S. epidermidis, C. albicans, P. aeruginosa and endotoxin were injected into each 10 bags of amino acid solution. After incubation for 24 and 72 hours, aspirates of 0.1 mL from 30 bags, with filtration and without filtration, were inoculated into culture media. The effluent from bags containing endotoxin was tested by limulus amebocyte lysate test. RESULTS: When effluents were filtered before culture, those from each 10 bags containing P. aeruginosa, C. albicans and endotoxin were sterile; also there was only one positive bacterial culture among 10 effluents from bags containing S. epidermidis. But by contrast all effluents without filtration showed positive cultures and endotoxin detection. CONCLUSION: This result showed that inline intravenous filters were useful device to remove bacteria, Candida, and bacterial endotoxin.
