Flavonoids from whole plants of Lagopsis supina.
- Author:
Jing ZHANG
;
Dao-ran PANG
;
Zheng HUANG
;
Hui-xia HUO
;
Yue-ting LI
;
Jiao ZHENG
;
Qian ZHANG
;
Yun-fang ZHAO
;
Peng-fei TU
;
Jun LI
- Publication Type:Journal Article
- MeSH:
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
Flavonoids;
chemistry;
isolation & purification;
Lamiaceae;
chemistry;
Molecular Structure;
Spectrometry, Mass, Electrospray Ionization
- From:
China Journal of Chinese Materia Medica
2015;40(16):3224-3228
- CountryChina
- Language:Chinese
-
Abstract:
The flavonoids were investigated from the whole plants of Lagopsis supina. The compounds were isolated and purified by various column chromatography, and their structures were identified by physiochemical properties and spectroscopic data. Two flavones were isolated from the CH2Cl2 layer of Lagopsis supina extract and identified as genkwanin (1) and 5-hydroxy-7,4'-dimethoxyflavone (2), respectively. Ten flavonoid glycosides were isolated from the water layer of Lagopsis supina and elucidated as kaempferol-3-O-6" (3-hydroxy-3-methylglutaryl) -β-D-glucoside (3), quercetin-3-O-6"-(3-hydroxy-3-methylglutaryl) -β-D-glucoside (4), quercetin-3-O-β-D-glucoside(5), kaempferol-3-Of3-D-glucoside ( 6), isorhamnetin-3-O-/-D-glycopyranoside (7), apigenin-7-O-6-D-glucoside (8), luteolin-7-O-β-D-glucoside (9), chrysoeriol-7-O-β-D-glucoside (10), rutin (11 ), and kaempferol-3-β-(6"-p-coumaroyl) -β-D-glucoside (tiliroside, 12). Compounds 3 and 4 were firstly isolated from Lamiaceae family, and compounds 1-12 were isolated from the plants of Lagopsis genus for the first time.
