Eudesmane sesquiterpenes from twigs of Manglietia hookeri.
- Author:
Mu-ge QI
;
Feng ZHANG
;
Wen-shu WANG
;
Hai-bo WU
;
Hao-chen YUAN
;
Yu-guo JIAO
;
Xu-jun DONG
- Publication Type:Journal Article
- MeSH:
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
Magnetic Resonance Spectroscopy;
Magnolia;
chemistry;
Molecular Structure;
Plant Stems;
chemistry;
Sesquiterpenes, Eudesmane;
chemistry;
isolation & purification;
Spectrometry, Mass, Electrospray Ionization
- From:
China Journal of Chinese Materia Medica
2015;40(16):3229-3232
- CountryChina
- Language:Chinese
-
Abstract:
Chemical constituents from the acetone extract of twigs of Manglietia hookeri were isolated and purified by various column chromatographic methods over silica gel and sephadex LH-20, and preparative TLC. The structures of these compounds were identified on the basis of physicochemical properties and spectral analysis, including NMR and MS spectra. Six eudesmane sesquiterpenes were obtained and their structures were identified as trans-eudesmane-4, 11-diol(1), β-eudesmol(2), (-) -10-epi-5β-hydroxy-β-eudesmol (3), epi-carrisone (4), 6-hydroxy-eudesm-4(14) -ene(5) and gynurenol(6). All the compounds were isolated from this plant for the first time. Furthermore, the 13C-NMR data of compound 3 were reported for the first time.
