Human papillomavirus genotypes in male patients attending the STD clinic in Zhenjiang area.
- Author:
Li-ming LI
;
Qin CHEN
;
Ming ZHANG
;
Fei-hu HU
;
Gao-fei XIAO
;
Jiang LIN
- Publication Type:Journal Article
- MeSH: China; DNA, Viral; Genotype; Humans; Male; Papillomaviridae; classification; Papillomavirus Infections; diagnosis; virology; Polymerase Chain Reaction
- From: National Journal of Andrology 2015;21(12):1102-1105
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the status of human papillomavirus ( HPV) infection and its genotypes in male patients in Zhenjiang area.
METHODSUsing PCR and reverse dot blot hybridization, we determined the genotypes of HPV DNA in 245 male patients at our Clinic of Dermatology and STD.
RESULTSThe total rate of HPV infection was 43.67% (107/245), and 18 subtypes were detected. Among the 107 HPV-positive cases, low-risk, high-risk, and combined high- and low-risk infections accounted for 39.25% (42/107), 38.32% (41/107), and 22.43% (24/107), respectively. The most notable low-risk HPV types were HPV6 and HPV11, and the most notable high-risk HPV types were HPV16, HPV52, and HPV58. The rates of single infection and multi-infection were 53.27% (57/107) and 46.73% (50/107), respectively. One case had the most types, infected with 8 genotypes. No statistically significant differences were observed in the total rate of HPV infection among different age groups (Χ2 = 7.999, P > 0.05).
CONCLUSIONThe dominant subtypes of HPV infection in male patients in Zhenjiang area were HPV6, HPV11, and HPV16. The most common subtypes were HPV6 and HPV11 in low-risk infection, and HPV16, HPV52, and HPV58 in high-risk infection.