Hydroa vacciniforme-like cutaneous T cell lymphoma: a case report and literature review.
- Author:
Hai-Ying LI
1
;
Huai-Li WANG
;
Tie-Zheng GAO
;
Zhi-Hong ZHUO
;
Dao-Ming LI
;
Hui-Xiang LI
Author Information
- Publication Type:Case Reports
- MeSH: Child, Preschool; Female; Humans; Hydroa Vacciniforme; pathology; Lymphoma, T-Cell, Cutaneous; drug therapy; immunology; pathology; Skin; pathology; Skin Neoplasms; drug therapy; immunology; pathology
- From: Chinese Journal of Contemporary Pediatrics 2009;11(7):596-598
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the clinical features, diagnosis and therapy of hydroa vacciniforme-like cutaneous T cell lymphoma.
METHODSThe clinical presentations and the findings of laboratory examinations and skin biopsy of affected tissue in a child with hydroa vacciniforme-like cutaneous T cell lymphoma were retrospectively reviewed.
RESULTSThe child manifested as rash, fever and lymph node intumesce. Rash was pantomorphia, including edematous erythema, vesicles, crusts, necrosis and depressed scar, and it was mild in winter and severe in summer, mainly involving in the face and extremities. Epstein-Barre virus (EBV)-IgM was positive. Histopathological findings revealed focal lymphocyte invasion in subcutaneous panniculus adiposus, mainly surrounding the blood vessels. Immunohistochemistry showed CD3 (+), CD43 (+), CD20 (-), pax-5 (-), TIA (+), CD5 (+), CD8 (+), Granmye (+) and CD4 (-). The clinical symptoms were improved after glucocorticoid treatment in this child.
CONCLUSIONSHydroa vacciniforme-like cutaneous T cell lymphoma has special clinical manifestations. This disorder may be definitely diagnosed by skin biopsy of affected tissue and immunohistochemistry assay. Glucocorticoid treatment is effective. EBV infection may be related to the development of this disorder.
